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Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits
Class C G protein–coupled receptors (GPCRs) are obligatory dimers that are particularly important for neuronal responses to endogenous and environmental stimuli. Ligand recognition through large extracellular domains leads to the reorganization of transmembrane regions to activate G protein signalin...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442050/ https://ncbi.nlm.nih.gov/pubmed/30723160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006173 |
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