DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma

BACKGROUND: DNA damage repair (DDR) alterations are important events in cancer initiation, progression, and therapeutic resistance. However, the involvement of DDR alterations in glioma malignancy needs further investigation. This study aims to characterize the clinical and molecular features of gli...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Meng, Xiangqi, Duan, Chunbin, Pang, Hengyuan, Chen, Qun, Han, Bo, Zha, Caijun, Dinislam, Magafurov, Wu, Pengfei, Li, Ziwei, Zhao, Shihong, Wang, Ruijia, Lin, Lin, Jiang, Chuanlu, Cai, Jinquan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Research paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442002/
https://ncbi.nlm.nih.gov/pubmed/30773478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.067
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