DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma

BACKGROUND: DNA damage repair (DDR) alterations are important events in cancer initiation, progression, and therapeutic resistance. However, the involvement of DDR alterations in glioma malignancy needs further investigation. This study aims to characterize the clinical and molecular features of gli...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Meng, Xiangqi, Duan, Chunbin, Pang, Hengyuan, Chen, Qun, Han, Bo, Zha, Caijun, Dinislam, Magafurov, Wu, Pengfei, Li, Ziwei, Zhao, Shihong, Wang, Ruijia, Lin, Lin, Jiang, Chuanlu, Cai, Jinquan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442002/
https://ncbi.nlm.nih.gov/pubmed/30773478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.067
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