ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma

Rationale: Glioma is the most common primary malignant brain tumor in adults. Chemoresistance of temozolomide (TMZ), the first-line chemotherapeutic agent, is a major issue in the management of patients with glioma. Alterations of alpha thalassemia/mental retardation syndrome X-linked (ATRX) gene co...

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Publicado en:Theranostics
Autores principales: Han, Bo, Meng, Xiangqi, Wu, Pengfei, Li, Ziwei, Li, Siyi, Zhang, Yangong, Zha, Caijun, Ye, Qile, Jiang, Chuanlu, Cai, Jinquan, Jiang, Tao
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053195/
https://ncbi.nlm.nih.gov/pubmed/32194873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41219
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