Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

Activation of receptor tyrosine kinase (RTK) protein is frequently observed in malignant progression of gliomas. In this study, the crosstalk activation of epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET) signaling pathways is demonstrated to contribute to t...

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Vydáno v:Nat Commun
Hlavní autoři: Meng, Xiangqi, Zhao, Yu, Han, Bo, Zha, Caijun, Zhang, Yangong, Li, Ziwei, Wu, Pengfei, Qi, Tengfei, Jiang, Chuanlu, Liu, Yang, Cai, Jinquan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992617/
https://ncbi.nlm.nih.gov/pubmed/32001707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14036-x
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