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Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

Activation of receptor tyrosine kinase (RTK) protein is frequently observed in malignant progression of gliomas. In this study, the crosstalk activation of epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET) signaling pathways is demonstrated to contribute to t...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Meng, Xiangqi, Zhao, Yu, Han, Bo, Zha, Caijun, Zhang, Yangong, Li, Ziwei, Wu, Pengfei, Qi, Tengfei, Jiang, Chuanlu, Liu, Yang, Cai, Jinquan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992617/
https://ncbi.nlm.nih.gov/pubmed/32001707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14036-x
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