Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

Activation of receptor tyrosine kinase (RTK) protein is frequently observed in malignant progression of gliomas. In this study, the crosstalk activation of epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET) signaling pathways is demonstrated to contribute to t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Meng, Xiangqi, Zhao, Yu, Han, Bo, Zha, Caijun, Zhang, Yangong, Li, Ziwei, Wu, Pengfei, Qi, Tengfei, Jiang, Chuanlu, Liu, Yang, Cai, Jinquan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992617/
https://ncbi.nlm.nih.gov/pubmed/32001707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14036-x
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