Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity

Exposure to elevated levels of manganese (Mn) causes manganism, a neurological disorder with similar characteristics to those of Parkinson’s disease (PD). Valproic acid (VPA), an antiepileptic, is known to inhibit histone deacetylases and exert neuroprotective effects in many experimental models of...

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Detaylı Bibliyografya
Yayımlandı:Neurotoxicology
Asıl Yazarlar: Johnson, James, Pajarillo, Edward, Karki, Pratap, Kim, Judong, Son, Deok-Soo, Aschner, Michael, Lee, Eunsook
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441963/
https://ncbi.nlm.nih.gov/pubmed/29778792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2018.05.001
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