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17β-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity
Chronic exposure to manganese (Mn) causes neurotoxicity, referred to as manganism, with common clinical features of parkinsonism. 17β-estradiol (E2) and tamoxifen (TX), a selective estrogen receptor modulator (SERM), afford neuroprotection in several neurological disorders, including Parkinson’s dis...
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| Publicado no: | Neurotoxicology |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5905416/ https://ncbi.nlm.nih.gov/pubmed/29183790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2017.11.008 |
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