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17β-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity

Chronic exposure to manganese (Mn) causes neurotoxicity, referred to as manganism, with common clinical features of parkinsonism. 17β-estradiol (E2) and tamoxifen (TX), a selective estrogen receptor modulator (SERM), afford neuroprotection in several neurological disorders, including Parkinson’s dis...

詳細記述

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書誌詳細
出版年:Neurotoxicology
主要な著者: Pajarillo, Edward, Johnson, James, Kim, Judong, Karki, Pratap, Son, Deok-Soo, Aschner, Michael, Lee, Eunsook
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905416/
https://ncbi.nlm.nih.gov/pubmed/29183790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2017.11.008
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