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Integrated epigenomic profiling reveals endogenous retrovirus reactivation in renal cell carcinoma

BACKGROUND: Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transcription factor (HIF) pathway. Despite intensive st...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Siebenthall, Kyle T., Miller, Chris P., Vierstra, Jeff D., Mathieu, Julie, Tretiakova, Maria, Reynolds, Alex, Sandstrom, Richard, Rynes, Eric, Haugen, Eric, Johnson, Audra, Nelson, Jemma, Bates, Daniel, Diegel, Morgan, Dunn, Douglass, Frerker, Mark, Buckley, Michael, Kaul, Rajinder, Zheng, Ying, Himmelfarb, Jonathan, Ruohola-Baker, Hannele, Akilesh, Shreeram
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441874/
https://ncbi.nlm.nih.gov/pubmed/30827930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.063
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