Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci

BACKGROUND: Linking genetic risk loci identified by genome-wide association studies (GWAS) to their causal genes remains a major challenge. Disease-associated genetic variants are concentrated in regions containing regulatory DNA elements, such as promoters and enhancers. Although researchers have p...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Sieber, Karsten B., Batorsky, Anna, Siebenthall, Kyle, Hudkins, Kelly L., Vierstra, Jeff D., Sullivan, Shawn, Sur, Aakash, McNulty, Michelle, Sandstrom, Richard, Reynolds, Alex, Bates, Daniel, Diegel, Morgan, Dunn, Douglass, Nelson, Jemma, Buckley, Michael, Kaul, Rajinder, Sampson, Matthew G., Himmelfarb, Jonathan, Alpers, Charles E., Waterworth, Dawn, Akilesh, Shreeram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2019
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405142/
https://ncbi.nlm.nih.gov/pubmed/30760496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018030309
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