PI3K inhibitors protect against glucocorticoid-induced skin atrophy

BACKGROUND: Skin atrophy is a major adverse effect of topical glucocorticoids. We recently reported that REDD1 (regulated in development and DNA damage 1) and FKBP51 (FK506 binding protein 5), negative regulators of mTOR/Akt signaling, are induced by glucocorticoids in mouse and human skin and are c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EBioMedicine
Prif Awduron: Agarwal, Shivani, Mirzoeva, Salida, Readhead, Ben, Dudley, Joel T., Budunova, Irina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Research paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441871/
https://ncbi.nlm.nih.gov/pubmed/30737086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.055
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