Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy

FKBP51 (FK506-binding protein 51) is a known co-chaperone and regulator of the glucocorticoid receptor (GR), which usually attenuates its activity. FKBP51 is one of the major GR target genes in skin, but its role in clinical effects of glucocorticoids is not known. Here, we used FKBP51 knockout (KO)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Baida, Gleb, Bhalla, Pankaj, Yemelyanov, Alexander, Stechschulte, Lance A., Shou, Weinian, Readhead, Ben, Dudley, Joel T., Sánchez, Edwin R., Budunova, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205168/
https://ncbi.nlm.nih.gov/pubmed/30410676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26194
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