REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids

Cutaneous atrophy is the major adverse effect of topical glucocorticoids; however, its molecular mechanisms are poorly understood. Here, we identify stress-inducible mTOR inhibitor REDD1 (regulated in development and DNA damage response 1) as a major molecular target of glucocorticoids, which mediat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Baida, Gleb, Bhalla, Pankaj, Kirsanov, Kirill, Lesovaya, Ekaterina, Yakubovskaya, Marianna, Yuen, Kit, Guo, Shuchi, Lavker, Robert M, Readhead, Ben, Dudley, Joel T, Budunova, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309667/
https://ncbi.nlm.nih.gov/pubmed/25504525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404601
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados