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REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids
Cutaneous atrophy is the major adverse effect of topical glucocorticoids; however, its molecular mechanisms are poorly understood. Here, we identify stress-inducible mTOR inhibitor REDD1 (regulated in development and DNA damage response 1) as a major molecular target of glucocorticoids, which mediat...
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| Udgivet i: | EMBO Mol Med |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309667/ https://ncbi.nlm.nih.gov/pubmed/25504525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404601 |
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