Effects of antibiotic component on in-vitro bacterial killing, physico-chemical properties, aerosolization and dissolution of a ternary-combinational inhalation powder formulation of antibiotics for pan-drug resistant Gram-negative lung infections

Combinational antibiotic formulations have emerged as an important strategy to combat antibiotic resistance. The main objective of this study was to examine effects of individual components on the antimicrobial activity, physico-chemical properties, aerosolization and dissolution of powder aerosol f...

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Veröffentlicht in:Int J Pharm
Hauptverfasser: Mangal, Sharad, Huang, Jiayang, Shetty, Nivedita, Park, Heejun, Lin, Yu-wei, Yu, Heidi H., Zemlyanov, Dmitry, Velkov, Tony, Li, Jian, Zhou, Qi (Tony)
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441383/
https://ncbi.nlm.nih.gov/pubmed/30797863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2019.02.018
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