Assembly and translocation of a CRISPR-Cas primed acquisition complex

CRISPR-Cas systems confer an adaptive immunity against viruses. Following viral injection, Cas1-Cas2 integrates segments of the viral genome (spacers) into the CRISPR locus. In addition, efficient “primed” spacer acqui sition and viral degradation (interference) both require the Cascade complex alon...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Dillard, Kaylee E., Brown, Maxwell W., Johnson, Nicole V., Xiao, Yibei, Dolan, Adam, Hernandez, Erik, Dahlhauser, Samuel D., Kim, Yoori, Myler, Logan R., Anslyn, Eric V., Ke, Ailong, Finkelstein, Ilya J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441324/
https://ncbi.nlm.nih.gov/pubmed/30343903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.039
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