Assembly and translocation of a CRISPR-Cas primed acquisition complex

CRISPR-Cas systems confer an adaptive immunity against viruses. Following viral injection, Cas1-Cas2 integrates segments of the viral genome (spacers) into the CRISPR locus. In addition, efficient “primed” spacer acqui sition and viral degradation (interference) both require the Cascade complex alon...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Dillard, Kaylee E., Brown, Maxwell W., Johnson, Nicole V., Xiao, Yibei, Dolan, Adam, Hernandez, Erik, Dahlhauser, Samuel D., Kim, Yoori, Myler, Logan R., Anslyn, Eric V., Ke, Ailong, Finkelstein, Ilya J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441324/
https://ncbi.nlm.nih.gov/pubmed/30343903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.039
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