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How Type II CRISPR-Cas establish immunity through Cas1-Cas2 mediated spacer integration
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and the nearby cas (CRISPR-associated) operon establish an RNA-based adaptive immunity system in prokaryotes(1–5). Molecular memory is created when a short foreign DNA-derived prespacer is integrated into the CRISPR array as a new sp...
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| 出版年: | Nature |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832332/ https://ncbi.nlm.nih.gov/pubmed/28869593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24020 |
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