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Hypoxia‐inducible factor‐1 α deletion in myeloid lineage attenuates hypoxia‐induced pulmonary hypertension

Hypoxemia is seen in patients with pulmonary hypertension and hypoxic pulmonary vasoconstriction worsens their clinical condition. However, vasoconstriction is not the only aspect through which hypoxia induces the progression to pulmonary hypertension. Hypoxia‐inducible factor‐1α (HIF‐1α) is a trans...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Kojima, Hiroshi, Tokunou, Tomotake, Takahara, Yusuke, Sunagawa, Kenji, Hirooka, Yoshitaka, Ichiki, Toshihiro, Tsutsui, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440913/
https://ncbi.nlm.nih.gov/pubmed/30927327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14025
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