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Hypoxia‐inducible factor‐1 α deletion in myeloid lineage attenuates hypoxia‐induced pulmonary hypertension

Hypoxemia is seen in patients with pulmonary hypertension and hypoxic pulmonary vasoconstriction worsens their clinical condition. However, vasoconstriction is not the only aspect through which hypoxia induces the progression to pulmonary hypertension. Hypoxia‐inducible factor‐1α (HIF‐1α) is a trans...

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Podrobná bibliografie
Vydáno v:Physiol Rep
Hlavní autoři: Kojima, Hiroshi, Tokunou, Tomotake, Takahara, Yusuke, Sunagawa, Kenji, Hirooka, Yoshitaka, Ichiki, Toshihiro, Tsutsui, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440913/
https://ncbi.nlm.nih.gov/pubmed/30927327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14025
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