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Hypoxia‐inducible factor‐1 α deletion in myeloid lineage attenuates hypoxia‐induced pulmonary hypertension

Hypoxemia is seen in patients with pulmonary hypertension and hypoxic pulmonary vasoconstriction worsens their clinical condition. However, vasoconstriction is not the only aspect through which hypoxia induces the progression to pulmonary hypertension. Hypoxia‐inducible factor‐1α (HIF‐1α) is a trans...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Kojima, Hiroshi, Tokunou, Tomotake, Takahara, Yusuke, Sunagawa, Kenji, Hirooka, Yoshitaka, Ichiki, Toshihiro, Tsutsui, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440913/
https://ncbi.nlm.nih.gov/pubmed/30927327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14025
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