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Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome

There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB index cases (HHCs) and a stringent non-human primate (NHP) challenge model, we ev...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Duffy, Fergal J., Weiner, January, Hansen, Scott, Tabb, David L., Suliman, Sara, Thompson, Ethan, Maertzdorf, Jeroen, Shankar, Smitha, Tromp, Gerard, Parida, Shreemanta, Dover, Drew, Axthelm, Michael K., Sutherland, Jayne S., Dockrell, Hazel M., Ottenhoff, Tom H. M., Scriba, Thomas J., Picker, Louis J., Walzl, Gerhard, Kaufmann, Stefan H. E., Zak, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440524/
https://ncbi.nlm.nih.gov/pubmed/30967866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00527
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