Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome

There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB index cases (HHCs) and a stringent non-human primate (NHP) challenge model, we ev...

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Опубликовано в: :Front Immunol
Главные авторы: Duffy, Fergal J., Weiner, January, Hansen, Scott, Tabb, David L., Suliman, Sara, Thompson, Ethan, Maertzdorf, Jeroen, Shankar, Smitha, Tromp, Gerard, Parida, Shreemanta, Dover, Drew, Axthelm, Michael K., Sutherland, Jayne S., Dockrell, Hazel M., Ottenhoff, Tom H. M., Scriba, Thomas J., Picker, Louis J., Walzl, Gerhard, Kaufmann, Stefan H. E., Zak, Daniel E.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440524/
https://ncbi.nlm.nih.gov/pubmed/30967866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00527
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