A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts

Biomarkers that predict who among recently Mycobacterium tuberculosis (MTB)-exposed individuals will progress to active tuberculosis are urgently needed. Intracellular microRNAs (miRNAs) regulate the host response to MTB and circulating miRNAs (c-miRNAs) have been developed as biomarkers for other d...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Duffy, Fergal J., Thompson, Ethan, Downing, Katrina, Suliman, Sara, Mayanja-Kizza, Harriet, Boom, W. Henry, Thiel, Bonnie, Weiner III, January, Kaufmann, Stefan H. E., Dover, Drew, Tabb, David L., Dockrell, Hazel M., Ottenhoff, Tom H. M., Tromp, Gerard, Scriba, Thomas J., Zak, Daniel E., Walzl, Gerhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908968/
https://ncbi.nlm.nih.gov/pubmed/29706954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00661
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