A prospective blood RNA signature for tuberculosis disease risk

BACKGROUND: Identification of blood biomarkers that prospectively predict progression of Mycobacterium tuberculosis infection to tuberculosis disease may lead to interventions that impact the epidemic. METHODS: Healthy, M. tuberculosis infected South African adolescents were followed for 2 years; bl...

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Veröffentlicht in:Lancet
Hauptverfasser: Zak, Daniel E., Penn-Nicholson, Adam, Scriba, Thomas J., Thompson, Ethan, Suliman, Sara, Amon, Lynn M., Mahomed, Hassan, Erasmus, Mzwandile, Whatney, Wendy, Hussey, Gregory D., Abrahams, Deborah, Kafaar, Fazlin, Hawkridge, Tony, Verver, Suzanne, Hughes, E. Jane, Ota, Martin, Sutherland, Jayne, Howe, Rawleigh, Dockrell, Hazel M., Boom, W. Henry, Thiel, Bonnie, Ottenhoff, Tom H.M., Mayanja-Kizza, Harriet, Crampin, Amelia C, Downing, Katrina, Hatherill, Mark, Valvo, Joe, Shankar, Smitha, Parida, Shreemanta K, Kaufmann, Stefan H.E., Walzl, Gerhard, Aderem, Alan, Hanekom, Willem A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392204/
https://ncbi.nlm.nih.gov/pubmed/27017310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(15)01316-1
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