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A prospective blood RNA signature for tuberculosis disease risk

BACKGROUND: Identification of blood biomarkers that prospectively predict progression of Mycobacterium tuberculosis infection to tuberculosis disease may lead to interventions that impact the epidemic. METHODS: Healthy, M. tuberculosis infected South African adolescents were followed for 2 years; bl...

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Detalhes bibliográficos
Publicado no:Lancet
Main Authors: Zak, Daniel E., Penn-Nicholson, Adam, Scriba, Thomas J., Thompson, Ethan, Suliman, Sara, Amon, Lynn M., Mahomed, Hassan, Erasmus, Mzwandile, Whatney, Wendy, Hussey, Gregory D., Abrahams, Deborah, Kafaar, Fazlin, Hawkridge, Tony, Verver, Suzanne, Hughes, E. Jane, Ota, Martin, Sutherland, Jayne, Howe, Rawleigh, Dockrell, Hazel M., Boom, W. Henry, Thiel, Bonnie, Ottenhoff, Tom H.M., Mayanja-Kizza, Harriet, Crampin, Amelia C, Downing, Katrina, Hatherill, Mark, Valvo, Joe, Shankar, Smitha, Parida, Shreemanta K, Kaufmann, Stefan H.E., Walzl, Gerhard, Aderem, Alan, Hanekom, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392204/
https://ncbi.nlm.nih.gov/pubmed/27017310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(15)01316-1
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