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A prospective blood RNA signature for tuberculosis disease risk

BACKGROUND: Identification of blood biomarkers that prospectively predict progression of Mycobacterium tuberculosis infection to tuberculosis disease may lead to interventions that impact the epidemic. METHODS: Healthy, M. tuberculosis infected South African adolescents were followed for 2 years; bl...

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Publicat a:Lancet
Autors principals: Zak, Daniel E., Penn-Nicholson, Adam, Scriba, Thomas J., Thompson, Ethan, Suliman, Sara, Amon, Lynn M., Mahomed, Hassan, Erasmus, Mzwandile, Whatney, Wendy, Hussey, Gregory D., Abrahams, Deborah, Kafaar, Fazlin, Hawkridge, Tony, Verver, Suzanne, Hughes, E. Jane, Ota, Martin, Sutherland, Jayne, Howe, Rawleigh, Dockrell, Hazel M., Boom, W. Henry, Thiel, Bonnie, Ottenhoff, Tom H.M., Mayanja-Kizza, Harriet, Crampin, Amelia C, Downing, Katrina, Hatherill, Mark, Valvo, Joe, Shankar, Smitha, Parida, Shreemanta K, Kaufmann, Stefan H.E., Walzl, Gerhard, Aderem, Alan, Hanekom, Willem A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392204/
https://ncbi.nlm.nih.gov/pubmed/27017310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(15)01316-1
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