Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome

There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB index cases (HHCs) and a stringent non-human primate (NHP) challenge model, we ev...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Duffy, Fergal J., Weiner, January, Hansen, Scott, Tabb, David L., Suliman, Sara, Thompson, Ethan, Maertzdorf, Jeroen, Shankar, Smitha, Tromp, Gerard, Parida, Shreemanta, Dover, Drew, Axthelm, Michael K., Sutherland, Jayne S., Dockrell, Hazel M., Ottenhoff, Tom H. M., Scriba, Thomas J., Picker, Louis J., Walzl, Gerhard, Kaufmann, Stefan H. E., Zak, Daniel E.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440524/
https://ncbi.nlm.nih.gov/pubmed/30967866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00527
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