FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias

Acute promyelocytic leukemia (APL) is often associated with activating FLT3 signaling mutations. These are highly related to hyperleukocytosis, a major adverse risk factor with chemotherapy-based regimens. APL is a model for oncogene-targeted therapies: all-trans retinoic acid (ATRA) and arsenic bot...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Esnault, Cécile, Rahmé, Ramy, Rice, Kim L., Berthier, Caroline, Gaillard, Coline, Quentin, Samuel, Maubert, Anne-Lise, Kogan, Scott, de Thé, Hugues
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2019
主題:
Myeloid Neoplasia
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440296/
https://ncbi.nlm.nih.gov/pubmed/30674471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-07-866095
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