An Investigation Into Rigidity-Activity Relationships in bisQAC Amphiphilic Antiseptics

Twenty-one mono- and biscationic quaternary ammonium amphiphiles (monoQACs and bisQACs) were rapidly prepared in order to investigate the effects of rigidity of a diamine core structure on antiseptic activity. As anticipated, bioactivity against a panel of 6 bacteria including MRSA strains was stron...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ChemMedChem
Prif Awduron: Kontos, Renee C., Schallenhammer, Stephanie A., Bentley, Brian S., Morrison, Kelly R., Feliciano, Javier A., Tasca, Julia A., Kaplan, Anna R., Bezpalko, Mark W., Kassel, Scott W., Wuest, William M., Minbiole, Kevin P. C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440202/
https://ncbi.nlm.nih.gov/pubmed/30358105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800622
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