An Investigation Into Rigidity-Activity Relationships in bisQAC Amphiphilic Antiseptics

Twenty-one mono- and biscationic quaternary ammonium amphiphiles (monoQACs and bisQACs) were rapidly prepared in order to investigate the effects of rigidity of a diamine core structure on antiseptic activity. As anticipated, bioactivity against a panel of 6 bacteria including MRSA strains was stron...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Kontos, Renee C., Schallenhammer, Stephanie A., Bentley, Brian S., Morrison, Kelly R., Feliciano, Javier A., Tasca, Julia A., Kaplan, Anna R., Bezpalko, Mark W., Kassel, Scott W., Wuest, William M., Minbiole, Kevin P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440202/
https://ncbi.nlm.nih.gov/pubmed/30358105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800622
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