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Trivalent Sulfonium Compounds (TSCs): Tetrahydrothiophene-based amphiphiles exhibit similar antimicrobial activity to analogous ammonium-based amphiphiles

Recent advances in the development of quaternary ammonium compounds (QACs) have focused on new structural motifs to increase bioactivity, but significantly less studied has been the change from ammonium- to sulfonium-based disinfectants. Herein, we report the synthesis of structurally analogous seri...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Feliciano, Javier A., Leitgeb, Austin J., Schrank, Cassandra L., Allen, Ryan A., Minbiole, Kevin P. C., Wuest, William M., Carden, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965331/
https://ncbi.nlm.nih.gov/pubmed/33516911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2021.127809
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