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Recent structural insights into PRC2 regulation and substrate binding

Polycomb group proteins are transcriptional repressors controlling gene expression patterns and maintaining cell type identity. The chemical modifications of histones and DNA by the regulated activity of chromatin modifying enzymes such as Polycomb help establish and maintain such expression pattern...

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Vydáno v:Biochemistry
Hlavní autoři: Kasinath, Vignesh, Poepsel, Simon, Nogales, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438374/
https://ncbi.nlm.nih.gov/pubmed/30451485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01064
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