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JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications
INTRODUCTION: Histone modification activity of the polycomb repressive complexes 1 and 2 (PRC1 and PRC2) is critical for the establishment and maintenance of gene expression patterns and, thus, to the maintenance of cell identity. Distinct classes of cofactor proteins are known to regulate the funct...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7993630/ https://ncbi.nlm.nih.gov/pubmed/33479123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc3393 |
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