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JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications

INTRODUCTION: Histone modification activity of the polycomb repressive complexes 1 and 2 (PRC1 and PRC2) is critical for the establishment and maintenance of gene expression patterns and, thus, to the maintenance of cell identity. Distinct classes of cofactor proteins are known to regulate the funct...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: Kasinath, Vignesh, Beck, Curtis, Sauer, Paul, Poepsel, Simon, Kosmatka, Jennifer, Faini, Marco, Toso, Daniel, Aebersold, Ruedi, Nogales, Eva
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993630/
https://ncbi.nlm.nih.gov/pubmed/33479123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc3393
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