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JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications

INTRODUCTION: Histone modification activity of the polycomb repressive complexes 1 and 2 (PRC1 and PRC2) is critical for the establishment and maintenance of gene expression patterns and, thus, to the maintenance of cell identity. Distinct classes of cofactor proteins are known to regulate the funct...

詳細記述

保存先:
書誌詳細
出版年:Science
主要な著者: Kasinath, Vignesh, Beck, Curtis, Sauer, Paul, Poepsel, Simon, Kosmatka, Jennifer, Faini, Marco, Toso, Daniel, Aebersold, Ruedi, Nogales, Eva
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993630/
https://ncbi.nlm.nih.gov/pubmed/33479123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc3393
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