Do Opiate Antagonists Interfere with the Clinical Benefits of Stimulants in ADHD? A Double-Blind, Placebo-Controlled Trial of the Mixed Opioid Receptor Antagonist Naltrexone

OBJECTIVE: Methylphenidate (MPH) activates mu opioid receptors, which are linked to euphoria. Mu opioid antagonists, such as naltrexone, may attenuate the euphoric effects of stimulants, thereby minimizing their abuse potential. This study assessed whether the combination of naltrexone with MPH is w...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Psychiatry
Main Authors: Spencer, Thomas J., Bhide, Pradeep, Zhu, Jinmin, Faraone, Stephen V., Fitzgerald, Maura, Yule, Amy M., Uchida, Mai, Spencer, Andrea E., Anna Hall, M, Koster, Ariana J., Biederman, Joseph
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438372/
https://ncbi.nlm.nih.gov/pubmed/28640990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4088/JCP.16m11012
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