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Do Opiate Antagonists Interfere with the Clinical Benefits of Stimulants in ADHD? A Double-Blind, Placebo-Controlled Trial of the Mixed Opioid Receptor Antagonist Naltrexone
OBJECTIVE: Methylphenidate (MPH) activates mu opioid receptors, which are linked to euphoria. Mu opioid antagonists, such as naltrexone, may attenuate the euphoric effects of stimulants, thereby minimizing their abuse potential. This study assessed whether the combination of naltrexone with MPH is w...
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| Publicado no: | J Clin Psychiatry |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6438372/ https://ncbi.nlm.nih.gov/pubmed/28640990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4088/JCP.16m11012 |
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