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Synthesis, Bioactivity, and Enzymatic Modification of Antibacterial Thiotetromycin Derivatives

Thiotetronate-containing natural products, including thiolactomycin, thiotetromycin, and thiotetroamide, are potent, broad-spectrum antibacterial compounds that target fatty acid synthesis in bacteria. Natural modifications at the C-5 dialkyl position in this molecular series result in pronounced bi...

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Publicat a:Org Biomol Chem
Autors principals: Rothe, Marlene L., Li, Jie, Garibay, Ernesto, Moore, Bradley S., McKinnie, Shaun M. K.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437001/
https://ncbi.nlm.nih.gov/pubmed/30869693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob03109f
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