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Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an N-prenyltransferase

Prenylation is a common biological reaction in all domains of life wherein prenyl diphosphate donors transfer prenyl groups onto small molecules as well as large proteins. The enzymes that catalyze these reactions are structurally distinct from ubiquitous terpene cyclases that, instead, assemble ter...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chekan, Jonathan R., McKinnie, Shaun M. K., Noel, Joseph P., Moore, Bradley S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293706/
https://ncbi.nlm.nih.gov/pubmed/32457155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001325117
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