Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom

Oceanic harmful algal blooms of Pseudo-nitzschia diatoms produce the potent mammalian neurotoxin domoic acid (DA). Despite decades of research, the molecular basis for its biosynthesis is not known. By using growth conditions known to induce DA production in Pseudo-nitzschia multiseries, we implemen...

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Bibliografiska uppgifter
I publikationen:Science
Huvudupphovsmän: Brunson, John K., McKinnie, Shaun M. K., Chekan, Jonathan R., McCrow, John P., Miles, Zachary D., Bertrand, Erin M., Bielinski, Vincent A., Luhavaya, Hanna, Oborník, Miroslav, Smith, G. Jason, Hutchins, David A., Allen, Andrew E., Moore, Bradley S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276376/
https://ncbi.nlm.nih.gov/pubmed/30262498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau0382
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