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Synthesis and Antibacterial Activity of Pyranmycin Derivatives with N-1 and O-6 Modifications
Continuing from our ongoing effort in modifying aminoglycoside antibiotics with the goal of counteracting drug resistant bacteria, we have further derivatized pyranmycin, a neomycin class aminoglycoside antibiotic, with modifications at O-6 and N-1 positions. The revealed SAR results demonstrated th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692305/ https://ncbi.nlm.nih.gov/pubmed/17870543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.08.059 |
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