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Investigation of the Regioselectivity for Staudinger Reaction and Its Application for the Synthesis of Aminoglycosides with N-1 Modification

The criteria for controlling the regioselectivity of Staudinger reduction of azides have been investigated. These findings enable a convenient direct N-1 modification of the perazidoneamine and perazidoribostamycin resulting in the synthesis of aminoglycoside antibiotics with activity against drug r...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Jie, Chiang, Fang-I, Chen, Hsiao-Nung, Chang, Cheng-Wei Tom
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553255/
https://ncbi.nlm.nih.gov/pubmed/17465564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo062588j
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