Circulating heparan sulfate fragments mediate septic cognitive dysfunction

Septic patients frequently develop cognitive impairment that persists beyond hospital discharge. The impact of sepsis on electrophysiological and molecular determinants of learning is underexplored. We observed that mice that survived sepsis or endotoxemia experienced loss of hippocampal long-term p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Hippensteel, Joseph A., Anderson, Brian J., Orfila, James E., McMurtry, Sarah A., Dietz, Robert M., Su, Guowei, Ford, Joshay A., Oshima, Kaori, Yang, Yimu, Zhang, Fuming, Han, Xiaorui, Yu, Yanlei, Liu, Jian, Linhardt, Robert J., Meyer, Nuala J., Herson, Paco S., Schmidt, Eric P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2019
Gaiak:
Concise Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436867/
https://ncbi.nlm.nih.gov/pubmed/30720464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124485
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