Subclonal STAT3 mutations solidify clonal dominance

T large granular lymphocyte leukemia (T-LGLL) is a clonal lymphoproliferative disorder that can arise in the context of pathologic or physiologic cytotoxic T-cell (CTL) responses. STAT3 mutations are often absent in typical T-LGLL, suggesting that in a significant fraction of patients, antigen-drive...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Kerr, Cassandra M., Clemente, Michael J., Chomczynski, Peter W., Przychodzen, Bartlomiej, Nagata, Yasunobu, Adema, Vera, Visconte, Valeria, Lichtin, Alan E., Mustjoki, Satu, Radivoyevitch, Tomas, Sekeres, Mikkael A., Maciejewski, Jaroslaw P.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Lymphoid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436009/
https://ncbi.nlm.nih.gov/pubmed/30898763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018027862
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