Novel CD19-targeted TriKE restores NK cell function and proliferative capacity in CLL

Chronic lymphocytic leukemia (CLL) is characterized by chronic clonal expansion of mature CD19-expressing B lymphocytes and global dysfunction of immune effectors, including natural killer (NK) cells. CLL remains incurable, and novel approaches to refractory CLL are needed. Our group has previously...

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Bibliografische gegevens
Gepubliceerd in:Blood Adv
Hoofdauteurs: Felices, Martin, Kodal, Behiye, Hinderlie, Peter, Kaminski, Michael F., Cooley, Sarah, Weisdorf, Daniel J., Vallera, Daniel A., Miller, Jeffrey S., Bachanova, Veronika
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2019
Onderwerpen:
Immunobiology and Immunotherapy
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436008/
https://ncbi.nlm.nih.gov/pubmed/30890546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018029371
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