161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

Myelodysplastic syndrome (MDS) is a clonal heterogeneous stem cell disorder driven by multiple genetic and epigenetic alterations resulting in ineffective hematopoiesis. MDS has a high frequency of immune suppressors, including myeloid-derived suppressor cells (MDSCs), that collectively result in a...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Sarhan, Dhifaf, Brandt, Ludwig, Felices, Martin, Guldevall, Karolin, Lenvik, Todd, Hinderlie, Peter, Curtsinger, Julie, Warlick, Erica, Spellman, Stephen R., Blazar, Bruce R., Weisdorf, Daniel J., Cooley, Sarah, Vallera, Daniel A., Önfelt, Björn, Miller, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020813/
https://ncbi.nlm.nih.gov/pubmed/29941459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012369
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