Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

Cysteinyl leukotriene receptor 1 antagonists (CysLT1RA) are frequently used as add-on medication for the treatment of asthma. Recently, these compounds have shown protective effects in cardiovascular diseases. This prompted us to investigate their influence on soluble epoxide hydrolase (sEH) and per...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Pharmacol
मुख्य लेखकों: Göbel, Tamara, Diehl, Olaf, Heering, Jan, Merk, Daniel, Angioni, Carlo, Wittmann, Sandra K., Buscato, Estel.la, Kottke, Ramona, Weizel, Lilia, Schader, Tim, Maier, Thorsten J., Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Proschak, Ewgenij, Kahnt, Astrid S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2019
विषय:
Pharmacology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435570/
https://ncbi.nlm.nih.gov/pubmed/30949053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00263
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