Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

Cysteinyl leukotriene receptor 1 antagonists (CysLT1RA) are frequently used as add-on medication for the treatment of asthma. Recently, these compounds have shown protective effects in cardiovascular diseases. This prompted us to investigate their influence on soluble epoxide hydrolase (sEH) and per...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Göbel, Tamara, Diehl, Olaf, Heering, Jan, Merk, Daniel, Angioni, Carlo, Wittmann, Sandra K., Buscato, Estel.la, Kottke, Ramona, Weizel, Lilia, Schader, Tim, Maier, Thorsten J., Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Proschak, Ewgenij, Kahnt, Astrid S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435570/
https://ncbi.nlm.nih.gov/pubmed/30949053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00263
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