The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis

ESSENTIALS: Heat shock protein 47 (HSP47), a collagen specific chaperone is present on the platelet surface. Collagen mediated platelet function was reduced following blockade or deletion of HSP47. GPVI receptor regulated signalling was reduced in HSP47 deficient platelets. Platelet HSP47 tethers to...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P., Sage, T., Ushioda, R., Nagata, K., Farndale, R. W., Gibbins, J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434988/
https://ncbi.nlm.nih.gov/pubmed/29512284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13998
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