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UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway

BACKGROUND: Human melanoma is a malignant tumor originated from melanocytes with high invasion, metastasis, and poor prognosis. In this study, the effects of naphthalimides UNBS5162 and amonafide on the properties of proliferation and apoptosis in human melanoma cells were confirmed. METHODS: Cell p...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Ye, Yingyi, Huang, Shuhong, Wu, Yingying
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434921/
https://ncbi.nlm.nih.gov/pubmed/30962721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S177623
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