TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4

BACKGROUND: There is growing evidence that tripartite motif-containing protein 44 (TRIM44) plays crucial role in tumor development. However, the underlying mechanism of this deubiquitinating enzyme remains unclear. METHODS: Large clinical samples were used to detect TRIM44 expression and its associa...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Wei, Chuan-Yuan, Wang, Lu, Zhu, Meng-Xuan, Deng, Xin-Yi, Wang, Dao-He, Zhang, Si-Min, Ying, Jiang-Hui, Yuan, Xin, Wang, Qiang, Xuan, Tian-Fan, He, An-Qi, Qi, Fa-Zhi, Gu, Jian-Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437891/
https://ncbi.nlm.nih.gov/pubmed/30922374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1138-7
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