Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge

BACKGROUND: There is no licensed vaccine against enterotoxigenic Escherichia coli (ETEC), a major cause of diarrhea-associated morbidity and mortality among infants and children in low-income countries and travelers. The results of this vaccination/challenge study demonstrate strong protection by an...

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Veröffentlicht in:Vaccine
Hauptverfasser: Harro, Clayton, Louis Bourgeois, A., Sack, David, Walker, Richard, DeNearing, Barbara, Brubaker, Jessica, Maier, Nicole, Fix, Alan, Dally, Len, Chakraborty, Subhra, Clements, John D., Saunders, Ingelise, Darsley, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434318/
https://ncbi.nlm.nih.gov/pubmed/30797634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.02.025
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